A wide range of inherited bleeding disorders are diagnosed and treated in the Ä¢¹½tvÊÓƵ Haemophilia Comprehensive Care Centre. These include:
- Haemophilia A and B
- Von Willebrand’s disease
- Deficiency of factors I, II, V, VII, X, XI, and XIII
- Platelet disorders, including Glanzmann’s thrombasthenia and Bernard Soulier syndrome
Most treatments for bleeding disorders involve intra-venous (into a vein) injections.
Treatment for haemophilia A and B is with recombinant clotting factor concentrates and there are several different brands in use. In the case of mild Haemophilia A, desmopressin (DDAVP) can sometimes be used.
Von Willebrand’s disease, depending on the type and severity, can be treated with desmopressin or plasma derived factor VIII, which contains von Willebrand factor.
Individual clotting factor concentrates do not exist for all possible deficiencies but where a factor concentrate does not exist, other products can be used.
Some platelet disorders will respond to platelet transfusion but others may require treatment with products such as recombinant Factor VIIa.