**This test is not routinely available. Please call the Duty Biochemist to discuss, 0113 39 26922 option 2**. Indication for requesting: to discriminate between alcohol-induced hepatotoxicity and liver disease of other origin. The majority of transferrin in the blood has 3-5 carbohydrate side-chains. CDT refers to transferrin with 0-2 sidechains, which usually represents < 2.6% of the total. Alcohol inhibits glycosyl transferase and stimulates sialidase enzymes in the liver, resulting in an increase of CDT in the blood. CDT is a more sensitive and specific indicator for recent consumption of alcohol than GGT. CDT remains in the circulation for 7-14 days. CDT may also be increased in advanced cholestatic liver disease due to reduced removal, and in carbohydrate deficient glycoprotein syndromes.
Tube
01 (SE) – Serum Gel
ID
Tests&Tubes0164
Additional information
Not available for requests relating to DVLA enquiries.
Turn around
Turnaround time stated by Sheffield Pru: 5 days.
Send to
Blood Sciences LGI
(Test referred to: Sheffield Protein Reference Unit (PRU).)
Contact
For further details please contact Ä¢¹½tvÊÓƵ Pathology customer services: [email protected].
Advice
Full Referred Test details logged internally on the referred test database [BSF2REC17003]
Download
Collection Con
Minimum Volume: 2ml serum. Instructions to lab: Centrifuge sample, separate serum and store in fridge
Sample REQ
Blood
Ref. Range Notes
0 – 2.6%
Units
%