Information taken from Newcastle website: The Brahms CT-proAVP assay measures the C-terminal precursor fragment of arginine vasopressin (AVP), otherwise known as copeptin. Copeptin is released on an equimolar basis with AVP and therefore measurement of serum/plasma copeptin provides a surrogate measure of AVP concentrations. Clinical indication for requesting: differential diagnosis of polyuria / polydipsia syndromes. Copeptin measurements are of most value when taken under an osmotic stimulus.
Tube
01 (SE) – Serum Gel
ID
Tests&Tubes0175
Availability
Additional Information
**Only available to Endocrinology. Requests should be discussed with the Duty Biochemist, 0113 39 26922, option 2** Please include clinical details and concurrent osmolality with all requests.
Turn Around
Turnaround time stated by Newcastle: 4 weeks.
Send to
Blood Sciences LGI
(Test referred to: Newcastle Royal Victoria Infirmary).
Contact
For further details please contact Ä¢¹½tvÊÓƵ Pathology customer services: [email protected].
Advice
Full information on all referred tests can be found on the referred tests information database, EQMS reference BSF2REC17003.
Collection Con
Instructions to lab: Centrifuge sample, separate serum and store in fridge. EDTA plasma or lithium heparin plasma also acceptable.
Minimum volume: 1 mL serum/plasma.
Frequency
Sample REQ
Blood.
Ref. Range Notes
No single reference range is applicable as copeptin varies according to plasma osmolality in normal individuals. An interpretive comment will be included with each report.