The Optometry and Ophthalmology department are involved in various research projects.
The following studies are in progress or due to start shortly:
ASTUTE studyÌý– Research into Adalimumab vs a placebo as an add-on to Standard Therapy for autoimmune Uveitis.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
CHROMEOS studyÌý– Research into the genetics of Achromatopsia.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
COAST study- Research comparing single or combination Intravitreal therapies for nAMD.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
GALE studyÌý– Research into the long term effects of Intra vitreal treatment (IVT) in Geographic Atrophy (dry AMD).ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
MEIRA (010) studyÌý– Research into the long term effects of patients having Gene therapy for X-linked Retinitis Pigmentosa.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
PARADIGM studyÌý– Research into the ocular effects of treatment vs. placebo for Osteoarthritis knee pain.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
PRECISE studyÌý– Research using Artificial intelligence to analyse scans to predict response to IVT for nAMD.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
All of the following studies have either closed or are close to closing (closed to recruitment).
DERBY studyÌý–Ìý Research intoÌýdrug therapy for patients with Non exudative (dry) maculopathy. Members of the Optometry team are certified Investigators of Visual Acuity measurementÌýÌý
MATE study –ÌýResearch into drug therapy for patients with Exudative (wet) maculopathy using the drug Aflibercept as standard treatment versus treat and extend. Members of the Optometry team are certified Investigators of Visual Acuity measurement
PANDA study –ÌýResearch into drug therapy for patients with Exudative (wet) maculopathy.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
RAVEN study –ÌýResearch into drug therapy for patients with Macular oedema due to Branch Retinal Vein Occlusion.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
RHINE study –ÌýResearch into drug therapy for patients withÌýDiabetic Macular Oedema.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
SCOPE study –ÌýResearch into drug therapy for patients with Non exudative (dry) maculopathy.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
TENAYA study –ÌýResearch into drug therapy for patients with Exudative (wet) maculopathy.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
THROMBO study –ÌýResearch into drug therapy for patients with Diabetic Macular Oedema.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
VICI study –ÌýResearch into drug therapy for patients with Central Serous Retinopathy.ÌýMembers of the Optometry team are certified Investigators of Visual Acuity measurement
XOLARIS study –ÌýResearch into Retinitis Pigmentosa. Members of the Optometry team are certified Investigators of Microperimetry, Visual Acuity and Contrast SensitivityÌýmeasurement.
Previous research has included:
Research into the use of tinted spectacles for retinal dystrophies
Research into drug therapy for Exudative (wet) Macular degeneration with:
AfliberceptÌý– members of the Optometry team are certified Investigators of VisualÌý AcuityÌý measurement
Anecortave Acetate – members of the Optometry team are Phase 3 Trial Certified Investigators of Visual Acuity and Contrast Sensitivity measurement
Macugen – members of the Optometry team are Investigators of Visual Acuity and Contrast Sensitivity measurement
Lucentis – members of the Optometry team are certified Investigators of Visual Acuity measurement
Research into drug therapy for Cystoid Macular Degeneration with:
Posurdex – members of the Optometry team are EMMES certified Investigators of Visual Acuity and Contrast Sensitivity
Lucentis versusÌýEylea versus Avastin – members of the Optometry team are certified Investigators of Visual Acuity measurement
Research into refractive and corneal surgery in conjunction with the External Link St. James’s LaserVision centre based at St. James’s University Hospital.
Research into drug therapy for diabetic retinopathy with:
AfliberceptÌý– members of the Optometry team are certified Investigators of Visual Acuity measurement